ASTM-E1073:2001 Edition

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E1073-01 Standard Test Method for Obtaining a Pharmacological Profile with Mice

Published By	Publication Date	Number of Pages
ASTM	2001	13

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Categories: 11.120.01 - Pharmaceutics in general, ASTM

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Description

ASTM E1073-01

Historical Standard: Standard Test Method for Obtaining a Pharmacological Profile with Mice

ASTM E1073

Scope

1.1 This test method is designed as a simple and inexpensive initial screening procedure for new compounds with unknown pharmacological properties, or for the comparative bioassay of new members of a chemical series with class reference standards. The test method, which is applicable to most pharmacologically active compounds including pesticides, will properly rank order both acute lethality and potency with a minimum expenditure of test material. It is intended as the first step in a multi-tiered development program.

1.2 This standard does not purport to address the safety problems associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.

Keywords

chemicals; ED50; LD50; manipulative tests; MED50; mice; nonmanipulative tests; pesticides; phamacology; toxicity

ICS Code

ICS Number Code 11.120.01 (Pharmaceutics in general)

DOI: 10.1520/E1073-01

Additional information

Standard Title	E1073-01 Standard Test Method for Obtaining a Pharmacological Profile with Mice
Published Code	ASTM
Publication Date	2001
Pages Count	13
ICS Codes	11.120.01 - Pharmaceutics in general